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March 2026

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India has the scientific talent, clinical expertise, and growing research ecosystem to lead the next wave of innovation in cell and gene therapy. The real question is no longer whether these transformative therapies will reach India—but whether India will help define how they are developed, manufactured, and made accessible to the world.

293 Trace - a qPCR (TaqMan-based) assay

293Trace is a qPCR (TaqMan-based) assay developed in-house for the sensitive and specific detection and quantification of HEK293/HEK293T DNA and other human DNA in biological samples. Targeting conserved regions of the human genome, it achieves picogram-level detection across a broad dynamic range.

The unique features of cellogen Therapeutics’ 293Trace USPs,

  • Ready-to-use master mix, primers, and DNA controls
  • Detection range: 0.3 pg/µL – 3000 pg/µL
  • AI-generated analysis via a secure portal for accurate, automated, and traceable quantification
  • Ensures compliance with WHO and ICH recommendations for residual host cell DNA (<10ng/dose, ≤200 bp)
  • Validated reagents and SOPs for reproducibility and regulatory consistency

#TeamCellogen to bring down the cost of LV by 90 %

293 Trace -  a qPCR (TaqMan-based) assay

As Cellogen Therapeutics prepares to launch India’s largest Lentiviral Vector (LV) manufacturing facility, the team is expanding by hiring scientific talent and administrative staff to support the upcoming unit. Lentiviral Vectors—critical for CAR-T and gene therapy research—are currently expensive imports. By manufacturing them domestically and converting research-grade LV into commercially available vectors, Cellogen aims to reduce costs by up to 90%, making advanced research more accessible in India.

Science Explained- Lentiviral Vectors

293 Trace -  a qPCR (TaqMan-based) assay

A Lentiviral Vector (LV) is a modified virus used in modern gene and cell therapies to deliver genetic material into living cells. Derived from the Lentivirus family, the vector is engineered so that disease-causing components are removed while retaining its ability to efficiently insert therapeutic genes into target cells.

This capability makes LV a critical tool in treatments such as CAR-T cell therapy and other forms of gene therapy. High-quality LV is essential because it ensures safe, efficient, and consistent gene delivery. Reliable vector manufacturing improves treatment effectiveness, supports large-scale clinical research, and enables the development of next-generation therapies for cancer, genetic disorders, and rare diseases.

News from across the world

Germany

CAR-T Therapy Shows Drug-Free Remission in Lupus – Researchers have reported that CAR-T cell therapy achieved long-term drug-free remission in patients with severe systemic lupus erythematosus. By engineering a patient’s T cells to eliminate autoreactive B cells, scientists were able to reset the immune system and stop disease activity. The findings suggest CAR-T therapies could move beyond oncology and become curative treatments for autoimmune diseases such as lupus and rheumatoid arthritis.

United States

Gene-Edited Pancreatic Cells Offer Hope for Type-1 Diabetes - Scientists have developed gene-edited pancreatic islet cells capable of producing insulin while evading immune rejection after transplantation. In early clinical studies, the engineered cells remained functional without triggering strong immune responses. This innovation could eliminate the need for lifelong immunosuppressive drugs and represents a promising step toward a scalable cell-based therapy that may provide a functional cure for Type-1 diabetes.

India

India’s Largest Lentiviral Vector Facility to Boost Gene Therapy Research Country - Cellogen Therapeutics is soon launching India’s largest Lentiviral Vector (LV) manufacturing facility, a major step for the country’s cell and gene therapy ecosystem. Lentiviral Vectors are critical tools used to deliver therapeutic genes in CAR-T and other advanced therapies. The facility is expected to strengthen domestic manufacturing capacity, support academic and biotech research, reduce dependence on imports, and accelerate the development of next-generation gene therapies in India.

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